The direct application of carboxylic acids as a traceless activation group for radical Michael additions has been accomplished via visible light-mediated photoredox catalysis. Photon-induced

Jun 01, 2004 · Designing a new anchoring group can be essential for synthesis success, especially for small molecules on solid supports. Many novel linkers have recently been developed. Traceless linkers can be excised efficiently and quantitatively when desired while leaving behind no trace of the solid-phase synthesis. Additional to water as H-bond donor present in our solvent mixture, we evaluated different activation modes for the LUMO lowering of carbonyl group, 22 including Schreiner's thiourea, 23 as well as different lanthanide-based, water-compatible Lewis acids. 24,25 Interestingly, the choice of the activation mode (entries 2 and 3), as well as the The direct application of carboxylic acids as a traceless activation group for radical Michael additions has been accomplished via visible light-mediated photoredox catalysis. Photon-induced The direct application of carboxylic acids as a traceless activation group for radical Michael additions has been accomplished via visible light-mediated photoredox catalysis. Photon-induced Jan 01, 2015 · Carboxylic acids as a traceless activation group for conjugate additions: a three-step synthesis of (±)-pregabalin. Aug 6, 2014 · Journal of the American Chemical Society 14.70 # 1 Lingling Chu H-Index: 21 The direct application of carboxylic acids as a traceless activation group for radical Michael additions has been accomplished via visible light-mediated photoredox catalysis. Photon-induced The cyano group was used as a traceless activation group for the [3+2] cycloaddition of azomethine ylides in a two-step process, thereby providing a highly effective approach to 5-unsubstituted pyrrolidines.

Sulfonyl as a Traceless Activation Group for Enantioselective Mannich Reaction Catalyzed by Thiourea to Access Chiral β-Aminophosphonates Yungui Peng* Key Laboratory of Applied Chemistry of Chongqing Municipality, School of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, P. R. of China Email: pengyungui@hotmail.com

Additional to water as H-bond donor present in our solvent mixture, we evaluated different activation modes for the LUMO lowering of carbonyl group, 22 including Schreiner's thiourea, 23 as well as different lanthanide-based, water-compatible Lewis acids. 24,25 Interestingly, the choice of the activation mode (entries 2 and 3), as well as the The direct application of carboxylic acids as a traceless activation group for radical Michael additions has been accomplished via visible light-mediated photoredox catalysis. Photon-induced The direct application of carboxylic acids as a traceless activation group for radical Michael additions has been accomplished via visible light-mediated photoredox catalysis. Photon-induced

traceless activation group that would (i) allow ð-neutral or ð-deficient substrates to function as suitable nucleophiles for iminium catalysis, while (ii) enabling site-specific alkylation of aromatic nucleophiles outside of the constraints of Friedel-Crafts regioselectivity. Herein we report the first use of vinyl and

May 14, 2008 · Jundong Li, Huaibo Zhao, Xunjin Jiang, Xiance Wang, Haiming Hu, Lei Yu, Yandong Zhang, The Cyano Group as a Traceless Activation Group for the Intermolecular [3+2] Cycloaddition of Azomethine Ylides: A Five‐Step Synthesis of (±)‐Isoretronecanol, Angewandte Chemie International Edition, 10.1002/anie.201500961, 54, 21, (6306-6310), (2015). Lingling Chu, Chisa Ohta, Zhiwei Zuo, David W. C. MacMillan, Carboxylic Acids as A Traceless Activation Group for Conjugate Additions: A Three-Step Synthesis of (±)-Pregabalin, Journal of the American Chemical Society, 10.1021/ja505964r, 136, 31, (10886-10889), (2014). The cyano group was used as a traceless activation group for the [3+2] cycloaddition of azomethine ylides in a two-step process, thereby providing a highly effective approach to 5-unsubstituted